It is recommended that patients with erectile dysfunction take Fildena 120 as needed, approximately one hour prior to engaging in sexual activities. On the other hand, sildenafil can be taken anywhere from four to five hours before sexual activity. Depending on effectiveness and tolerance, the dose may be reduced to Fildena 120 or increased to the highest recommended dose of Fildena . The highest recommended frequency is one dosage per day.Elevated plasma levels of sildenafil are linked to age over 65, hepatic impairment, severe renal impairment, and concurrent use of potent cytochrome P450 3A4 inhibitors (ketoconazole, itraconazole, erythromycin, saquinavir).
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